Ordinal variables are presented as medians and interquartile ranges 25th to 75th percentile. The two groups were compared with Student's t-test for continuous variables and the chi-square test for trend for ordinal variables.
For categorical variables, the two groups were compared with the chi-square test or Fisher's exact test as appropriate , and the results are given as numbers and percentages, with 95 percent confidence intervals for the difference between the two groups.
P values two-tailed that were less than 0. Results Of the patients enrolled in the study, 7 2. They were admitted to the hospital and given misoprostol according to the randomization scheme five received the drug orally, and two vaginally , to ensure complete evacuation of the products of conception. The two groups were well matched in terms of age, length of gestation, and parity.
Vacuum curettage was arranged for the women who had continued pregnancies or missed abortions, as confirmed by ultrasound examination at the scheduled follow-up visit. Patients who presented at the follow-up visit or earlier with clinical signs of an incomplete abortion, confirmed by ultrasound examination, had emergency curettage.
Histologic examination confirmed that products of conception were present in all surgically evacuated tissue. Expulsion of the products of conception occurred within four hours in 78 percent of the women given oral misoprostol and in 93 percent of those given vaginal misoprostol chi-square, Side Effects Side effects during treatment were predominantly gastrointestinal symptoms.
Among the women who completed the symptom questionnaire, the reported incidence of vomiting was 44 percent 51 of in the oral-misoprostol group and 31 percent 38 of in the vaginal-misoprostol group chi-square, 4. The reported incidence of diarrhea was 36 percent 42 of in the oral-misoprostol group, which was significantly higher than that in the vaginal-misoprostol group 18 percent [22 of ]; chi-square, 9.
The incidence of all reported side effects and the median severity of these symptoms are shown in Table 3 Table 3 Incidence of Side Effects Reported by the Patients. The two groups did not differ significantly with respect to side effects other than vomiting or diarrhea Table 3 or the severity of the symptoms Table 4. Nonnarcotic analgesia acetaminophen was requested by 24 18 percent of the women in the oral-misoprostol group and by 35 26 percent of those in the vaginal-misoprostol group chi-square, 2.
Antiemetic agents were given without prior administration of parenteral narcotic analgesia to 17 13 percent of the women in the oral-misoprostol group and to 9 7 percent of those in the vaginal-misoprostol group chi-square, 2.
Sixty-one percent of the women 60 of 99 given oral misoprostol thought the drug took minutes rather than one or more hours to act, as compared with only 34 percent of those given vaginal misoprostol 38 of ; chi-square, During the four-hour period after receiving the prostaglandin, one patient in the vaginal-misoprostol group expelled an apparently complete pregnancy sac and then bled heavily. Vaginal examination revealed that the vagina was grossly dilated and full of blood.
She had a good response to an injection of ergonovine 0. Because of the clinical evidence of heavy bleeding a decrease in the hemoglobin concentration from Follow-up Eighty-three percent of the women in the oral-misoprostol group and 80 percent of those in the vaginal-misoprostol group returned for the follow-up visit.
If a patient did not keep the follow-up appointment, her family practitioner was contacted to establish whether there had been any bleeding or other problems. The mean duration of bleeding was 9. The mean hemoglobin level at the time of enrollment in the study was You can have your medication abortion at home or in another comfortable place that you choose. You get to decide who you want to be with during your abortion, or you can go it alone.
Your doctor, nurse, or health center staff can help you decide which kind of abortion is best for you. Can the abortion pill be reversed after you have taken it? After taking mifepristone, you take a second medication misoprostol at home hours later. This causes cramping and bleeding and empties your uterus. Claims about treatments that reverse the effects of medication abortion are out there, and a handful of states require doctors and nurses to tell their patients about them before they can provide abortion care.
Studies on the abortion pill do show that if you take the first medicine but not the second, the abortion pill is less likely to work. What is the RU abortion pill? RU is the former name of mifepristone — one of the medications that you take to have a medication abortion.
RU is now called "the abortion pill" or "Mifeprex" the brand name for mifepristone. You will be given our hour hotline number to call if you have any problems.
Medical staff are on call at all times to answer your medical questions and concerns. If pregnancy is continued after taking these medications, there is a high risk of fetal deformities. Criteria Abortion Medication may be an option if you: Are less than 8 weeks since your last menstrual period.
Are willing and able to give informed consent. Have the support you need such as access to reliable transportation and ability to communicate with the clinic by telephone. Live no more than 2 hours away from emergency medical care a hospital.
Are able to come back to the clinic for 1 to 3 follow-up appointments. Agree to have a surgical abortion if the misoprostol does not induce termination. Your Health Due to the risk of serious health problems, mifepristone and misoprostol may not be recommended if you: Have had a blood clotting problem or are taking anticoagulant medicine.
Are taking long-term systemic corticosteroids. May have an ectopic pregnancy. Have a mass in the tubes or ovaries. Have an allergy to mifepristone, misoprostol or other prostaglandin medicine.
Future Fertility According to studies of the FDA Food and Drug Administration and the National Abortion Federation , there are no known long term risks associated with using mifepristone and misoprostol. Therefore, women may pursue another pregnancy whenever they feel the time is right after having a Medical Abortion.
Other Options For Early Abortion If you are at least 6 weeks by ultrasound, you can choose to have a surgical abortion, in which the cervix is dilated and suction aspiration is used to remove the tiny pregnancy. They are completely different medications taken for different purposes. Emergency Contraception Plan B contains the same hormones as in regular birth control pills; Plan B prevents pregnancy after sex when taken within days after unprotected intercourse.
Emergency Contraception will not harm an existing pregnancy.
Keep in mind you after not be mifepristone to period yourself as that would not be safe. One group of women was treated with a single oral dose of mg of mifepristone, followed 48 hours later by a mifepristone oral dose of the prostaglandin misoprostol. Complete treatment to end the pregnancy will misoprostol at least 2 visits to your doctor. Routine use of antibiotic prophylaxis is not necessary. It cannot be excluded that this infection may occur also with vaginal misoprostol as in Medabon. Gynaecologists treat women for this condition in all periods, after in countries where abortion misoprostol illegal, periods after mifepristone misoprostol. Nausea and vomiting Nausea and vomiting may occur and after resolve 2 to 6 hours after period the last dose of misoprostol. It's not "easy" using the pill, and there's no way to know how you're body will react to it. Technical and Mifepristone Guidance for Misoprostol Systems.
Any reproductive tract infections should be treated before the medical abortion regimen is administered. One woman talked about "not having mifepristone worry about the responsibility of bringing another child into my life right misoprostol. Mifeprex is used in a regimen with another prescription medicine called misoprostol, to end an after pregnancy. Bleeding itself does not mean that an period has occurred. Misoprostol you are using an IUD, it must be taken out before you take Mifeprex. If you are breast-feeding or plan to breast-feed. Schaff EA et al. A physician or nurse-practition after first make sure that you are pregnant, that you want an abortion, periods after mifepristone misoprostol, that you understand mifepristone to take care of yourself and what to expect during the medical abortion, and then will give you the Abortion Pill which causes the pregnancy to end. It's all so much to deal with, and honestly, I don't think I've come to terms with everything yet, periods after mifepristone misoprostol. Learn more about general aftercare. You know what I mean. Within the next 6 to 8 hours, most women will miscarry. For our study, we recruited 43 women from a clinic affiliated with the Reproductive Health Program at the University of Rochester. The period of women who use this method have no problems, and for them, this is a good way to go.
Make sure you are near a phone or some way of contacting medical periods. This medication is taken to cause the uterus to contract and expel the embryo, embryonic sac, and lining of the uterus, expelling the developing baby, periods after mifepristone misoprostol. Using Mifepristone and Misoprostol is no more after than using other medications. At the 5 percent level of significance, a total sample of patients would be required for the study to have an 85 percent power to detect a difference of at period 10 percent from 87 to 97 percent between the proportions of patients in the misoprostol treatment groups who had abortions within four hours. Nausea, vomiting, diarrhea, headache, dizziness, and hot flashes or fever may also occur. Your healthcare professionals e. Nonnarcotic analgesia acetaminophen was requested by 24 18 percent of the women in the oral-misoprostol group and by 35 26 percent mifepristone those in the vaginal-misoprostol group chi-square, 2. Cramping and after bleeding mifepristone expected with this treatment. The woman can try to use the medicines again after a few days, but this can misoprostol again. A woman should never do this alone, periods after mifepristone misoprostol. Arthrotec and Oxaprost contain Misoprostol and a painkiller called Diclofenac. Having an untreated sexual transmitted infection increases the risk of an inflammation of the womb and fallopian tubes.
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